Would you use an HIV-preventing enema or rectal PrEP?
clinical trial tested whether people would be happy to insert rectal microbicides—an experimental HIV-prevention strategy—inside their butt before anal sex.Rectal microbicides are not PrEP drugs, but a different form of HIV-prevention medicine that works on anal and rectal tissue before sex.
Until now, it’s very difficult to apply microbicidal gel far enough inside the rectum to provide good protection. That’s why researchers are exploring other routes of delivery.They gave their test subjects three methods of anal insertion: Enemas, suppositories, and rectal inserts.
From the images they included, there’s not a huge difference between a suppository and an insert besides size.In each case, placebos were used.
The study wanted to determine if people were happy with insertion methods. It was not looking at the effectiveness of the drugs.The most popular form of insertion proved to be enemas and rectal inserts.
